Chimeric Japanese Encephalitis Virus SA14/SA14-14-2 Was Virulence Attenuated and Protected the Challenge of Wild-Type Strain SA14

The attenuated Japanese encephalitis virus (JEV) live vaccine SA14-14-2 prepared from wild-type (WT) strain SA14 was licensed to prevent Japanese encephalitis (JE) in 1989 in China. Many studies showed that the premembrane (prM) and envelope (E) protein were the crucial determinant of virulence and...

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Dades bibliogràfiques
Publicat a:Can J Infect Dis Med Microbiol
Autors principals: Huang, Rong, Leng, Shengling, Feng, Yalan, Tang, Liping, Yuan, Lei, Yang, Jian
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421771/
https://ncbi.nlm.nih.gov/pubmed/30944684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9179308
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