Chimeric Japanese Encephalitis Virus SA14/SA14-14-2 Was Virulence Attenuated and Protected the Challenge of Wild-Type Strain SA14

The attenuated Japanese encephalitis virus (JEV) live vaccine SA14-14-2 prepared from wild-type (WT) strain SA14 was licensed to prevent Japanese encephalitis (JE) in 1989 in China. Many studies showed that the premembrane (prM) and envelope (E) protein were the crucial determinant of virulence and...

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Enregistré dans:
Détails bibliographiques
Publié dans:Can J Infect Dis Med Microbiol
Auteurs principaux: Huang, Rong, Leng, Shengling, Feng, Yalan, Tang, Liping, Yuan, Lei, Yang, Jian
Format: Artigo
Langue:Inglês
Publié: Hindawi 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421771/
https://ncbi.nlm.nih.gov/pubmed/30944684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9179308
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