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Identification and functional prediction of mitochondrial complex III and IV mutations associated with glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary brain tumor in adults, with a dismal prognosis. Treatment is hampered by GBM's unique biology, including differential cell response to therapy. Although several mitochondrial abnormalities have been identified, how mitochondrial DNA (mtD...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Lloyd, Rhiannon E., Keatley, Kathleen, Littlewood, D. Timothy J., Meunier, Brigitte, Holt, William V., An, Qian, Higgins, Samantha C., Polyzoidis, Stavros, Stephenson, Katie F., Ashkan, Keyoumars, Fillmore, Helen L., Pilkington, Geoffrey J., McGeehan, John E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474231/
https://ncbi.nlm.nih.gov/pubmed/25731774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov020
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