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Targeting matrix metalloproteinases in cancer: Bringing new life to old ideas

Since the identification of matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, as being a driving factor for cancer progression and patient prognosis, MMPs have been studied extensively. Although early programs targeting MMPs were largely unsuccessful in clinical trials, th...

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Detalhes bibliográficos
Publicado no:Genes Dis
Main Authors: Cathcart, Jillian, Pulkoski-Gross, Ashleigh, Cao, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Chongqing Medical University 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474140/
https://ncbi.nlm.nih.gov/pubmed/26097889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2014.12.002
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