Inhibition of Matrix Metalloproteinase 14 (MMP-14)-mediated Cancer Cell Migration

Matrix metalloproteinases (MMPs) have been shown to be key players in both extracellular matrix remodeling and cell migration during cancer metastasis. MMP-14, a membrane-anchored MMP, in particular, is closely associated with these processes. The hemopexin (PEX) domain of MMP-14 has been proposed a...

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Main Authors: Zarrabi, Kevin, Dufour, Antoine, Li, Jian, Kuscu, Cem, Pulkoski-Gross, Ashleigh, Zhi, Jizu, Hu, Youjun, Sampson, Nicole S., Zucker, Stanley, Cao, Jian
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190951/
https://ncbi.nlm.nih.gov/pubmed/21795678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256644
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