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Conversion of Stationary to Invasive Tumor Initiating Cells (TICs): Role of Hypoxia in Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) Trafficking

Emerging evidence has implicated the role of tumor initiating cells (TICs) in the process of cancer metastasis. The mechanism underlying the conversion of TICs from stationary to invasive remains to be characterized. In this report, we employed less invasive breast cancer TICs, SK-3rd, that displays...

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Библиографические подробности
Главные авторы: Li, Jian, Zucker, Stanley, Pulkoski-Gross, Ashleigh, Kuscu, Cem, Karaayvaz, Mihriban, Ju, Jingfang, Yao, Herui, Song, Erwei, Cao, Jian
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367975/
https://ncbi.nlm.nih.gov/pubmed/22679501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038403
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