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Conversion of Stationary to Invasive Tumor Initiating Cells (TICs): Role of Hypoxia in Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) Trafficking

Emerging evidence has implicated the role of tumor initiating cells (TICs) in the process of cancer metastasis. The mechanism underlying the conversion of TICs from stationary to invasive remains to be characterized. In this report, we employed less invasive breast cancer TICs, SK-3rd, that displays...

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Detalhes bibliográficos
Main Authors: Li, Jian, Zucker, Stanley, Pulkoski-Gross, Ashleigh, Kuscu, Cem, Karaayvaz, Mihriban, Ju, Jingfang, Yao, Herui, Song, Erwei, Cao, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367975/
https://ncbi.nlm.nih.gov/pubmed/22679501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038403
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