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Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice

AIMS/HYPOTHESIS: The identification of novel targets that stimulate endogenous regeneration of beta cells would represent a significant advance in the treatment of patients with diabetes. The betatrophin hypothesis suggests that increased expression of angiopoietin-like protein 8 (ANGPTL8) induces d...

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Bibliografiske detaljer
Udgivet i:Diabetologia
Main Authors: Cox, Aaron R., Lam, Carol J., Bonnyman, Claire W., Chavez, Julia, Rios, Jacqueline S., Kushner, Jake A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473078/
https://ncbi.nlm.nih.gov/pubmed/25917759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3590-z
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