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Retinal Flip in Rhodopsin Activation?
Rhodopsin is a well-characterized structural model of a G protein-coupled receptor. Photoisomerization of the covalently bound retinal triggers activation. Surprisingly, the x-ray crystal structure of the active Meta-II state has a 180° rotation about the long-axis of the retinal polyene chain. Unbi...
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| Udgivet i: | Biophys J |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472225/ https://ncbi.nlm.nih.gov/pubmed/26083914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.04.040 |
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