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Molecular Simulations and Solid-State NMR Investigate Dynamical Structure in Rhodopsin Activation
Rhodopsin has served as the primary model for studying G protein-coupled receptors (GPCRs)—the largest group in the human genome, and consequently a primary target for pharmaceutical development. Understanding the functions and activation mechanisms of GPCRs has proven to be extraordinarily difficul...
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| Udgivet i: | Biochim Biophys Acta |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5270601/ https://ncbi.nlm.nih.gov/pubmed/21851809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.08.003 |
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