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Molecular Simulations and Solid-State NMR Investigate Dynamical Structure in Rhodopsin Activation

Rhodopsin has served as the primary model for studying G protein-coupled receptors (GPCRs)—the largest group in the human genome, and consequently a primary target for pharmaceutical development. Understanding the functions and activation mechanisms of GPCRs has proven to be extraordinarily difficul...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Mertz, Blake, Struts, Andrey V., Feller, Scott E., Brown, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270601/
https://ncbi.nlm.nih.gov/pubmed/21851809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.08.003
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