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Retinal Ligand Mobility Explains Internal Hydration and Reconciles Active Rhodopsin Structures

Rhodopsin, the mammalian dim-light receptor, is one of the best-characterized G-protein-coupled receptors, a pharmaceutically important class of membrane proteins that has garnered a great deal of attention because of the recent availability of structural information. Yet the mechanism of rhodopsin...

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Hlavní autoři: Leioatts, Nicholas, Mertz, Blake, Martínez-Mayorga, Karina, Romo, Tod D., Pitman, Michael C., Feller, Scott E., Grossfield, Alan, Brown, Michael F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096112/
https://ncbi.nlm.nih.gov/pubmed/24328554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4013947
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