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Steric and Electronic Influences on the Torsional Energy Landscape of Retinal

We have performed quantum mechanical calculations for retinal model compounds to establish the rotational energy barriers for the C5-, C9-, and C13-methyl groups known to play an essential role in rhodopsin activation. Intraretinal steric interactions as well as electronic effects lower the rotation...

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Detalhes bibliográficos
Main Authors: Mertz, Blake, Lu, Michael, Brown, Michael F., Feller, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145276/
https://ncbi.nlm.nih.gov/pubmed/21806916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.06.020
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