Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells

Glycogen synthase kinase-3 (Gsk-3) is a key regulator of multiple signal transduction pathways. Recently we described a novel role for Gsk-3 in the regulation of DNA methylation at imprinted loci in mouse embryonic stem cells (ESCs), suggesting that epigenetic changes regulated by Gsk-3 are likely a...

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Pubblicato in:Mol Biol Cell
Autori principali: Meredith, Gavin D., D'Ippolito, Anthony, Dudas, Miroslav, Zeidner, Leigh C., Hostetter, Logan, Faulds, Kelsie, Arnold, Thomas H., Popkie, Anthony P., Doble, Bradley W., Marnellos, George, Adams, Christopher, Wang, Yulei, Phiel, Christopher J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472022/
https://ncbi.nlm.nih.gov/pubmed/25833708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-01-0013
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