Rhinacanthin C Inhibits Osteoclast Differentiation and Bone Resorption: Roles of TRAF6/TAK1/MAPKs/NF-κB/NFATc1 Signaling

Rhinacanthin C is a naphthoquinone ester with anti-inflammatory activity, found in Rhinacanthus nasutus (L) Kurz (Acanthaceae). We found that rhinacanthin C inhibited osteoclast differentiation stimulated by the receptor activator of nuclear factor-κB ligand (RANKL) in mouse bone marrow macrophage c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tomomura, Mineko, Suzuki, Ryuichiro, Shirataki, Yoshiaki, Sakagami, Hiroshi, Tamura, Nobuaki, Tomomura, Akito
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471279/
https://ncbi.nlm.nih.gov/pubmed/26083531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130174
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