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(+)-Vitisin A Inhibits Osteoclast Differentiation by Preventing TRAF6 Ubiquitination and TRAF6-TAK1 Formation to Suppress NFATc1 Activation

We recently reported that oral administration of a (+)-vitisin A-enriched product prepared from Vitis thunbergii obviously ameliorated bone loss in ovariectomized mice and (+)-vitisin A was able to inhibit receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation in RAW264.7 cell...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chiou, Wen-Fei, Huang, Yu-Ling, Liu, Yen-Wenn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928435/
https://ncbi.nlm.nih.gov/pubmed/24558484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089159
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