Serum Calcium-decreasing Factor, Caldecrin, Inhibits Osteoclast Differentiation by Suppression of NFATc1 Activity

Caldecrin/chymotrypsin C is a novel secretory-type serine protease that was originally isolated as a serum calcium-decreasing factor from the pancreas. Previously, we reported that caldecrin suppressed the bone-resorbing activity of rabbit mature osteoclasts (Tomomura, A., Yamada, H., Fujimoto, K.,...

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Detalhes bibliográficos
Main Authors: Hasegawa, Hiroya, Kido, Seisui, Tomomura, Mineko, Fujimoto, Kengo, Ohi, Michi, Kiyomura, Masaru, Kanegae, Haruhide, Inaba, Akemi, Sakagami, Hiroshi, Tomomura, Akito
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919108/
https://ncbi.nlm.nih.gov/pubmed/20547767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068742
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