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Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors

BACKGROUND: Whether biomechanical force on the heart can induce exosome secretion to modulate cardiovascular function is not known. We investigated the secretion and activity of exosomes containing a key receptor in cardiovascular function, the Angiotensin II Type I Receptor (AT1R). METHODS AND RESU...

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Bibliografiske detaljer
Udgivet i:Circulation
Main Authors: Pironti, Gianluigi, Strachan, Ryan T., Abraham, Dennis, Yu, Samuel Mon-Wei, Chen, Minyong, Chen, Wei, Hanada, Kenji, Mao, Lan, Watson, Lewis J., Rockman, Howard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470842/
https://ncbi.nlm.nih.gov/pubmed/25995315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.015687
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