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PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity

Fibrosis is a common disease process in which profibrotic cells disturb organ function by secreting disorganized extracellular matrix (ECM). Adipose tissue fibrosis occurs during obesity and is associated with metabolic dysfunction, but how profibrotic cells originate is still being elucidated. Here...

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書目詳細資料
發表在:Genes Dev
Main Authors: Iwayama, Tomoaki, Steele, Cameron, Yao, Longbiao, Dozmorov, Mikhail G., Karamichos, Dimitris, Wren, Jonathan D., Olson, Lorin E.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470280/
https://ncbi.nlm.nih.gov/pubmed/26019175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.260554.115
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