Review of Tolvaptan’s Pharmacokinetic and Pharmacodynamic Properties and Drug Interactions

Tolvaptan is an arginine vasopressin (AVP) antagonist that acts to increase excretion of free water (aquaresis) in patients without introducing electrolyte abnormalities or worsening renal function. It works via blockade of vasopressin-2 receptors at the renal collecting duct. Since the approval of...

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Pubblicato in:J Clin Med
Autori principali: Bhatt, Purav R., McNeely, Elizabeth B., Lin, Tess E., Adams, Kirkwood F., Patterson, J. Herbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2014
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470182/
https://ncbi.nlm.nih.gov/pubmed/26237603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm3041276
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