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Pharmacokinetics and pharmacodynamics of oral tolvaptan in patients with varying degrees of renal function
The selective vasopressin V2–receptor antagonist tolvaptan is eliminated almost exclusively by non-renal mechanisms. As renal impairment can influence the pharmacokinetics of drugs even when eliminated by non-renal mechanisms, we evaluated the effect of renal insufficiency on the pharmacokinetics/ph...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973039/ https://ncbi.nlm.nih.gov/pubmed/24048380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.350 |
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