Review of Tolvaptan’s Pharmacokinetic and Pharmacodynamic Properties and Drug Interactions

Tolvaptan is an arginine vasopressin (AVP) antagonist that acts to increase excretion of free water (aquaresis) in patients without introducing electrolyte abnormalities or worsening renal function. It works via blockade of vasopressin-2 receptors at the renal collecting duct. Since the approval of...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Med
Auteurs principaux: Bhatt, Purav R., McNeely, Elizabeth B., Lin, Tess E., Adams, Kirkwood F., Patterson, J. Herbert
Format: Artigo
Langue:Inglês
Publié: MDPI 2014
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470182/
https://ncbi.nlm.nih.gov/pubmed/26237603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm3041276
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