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Lipoic acid decreases Mcl-1, Bcl-x(L) and up regulates Bim on ovarian carcinoma cells leading to cell death
BACKGROUND: Ovarian carcinoma is the leading cause of death from gynecological cancer because there is risk of chemoresistance. As previously demonstrated in our laboratory, Alpha-lipoic acid (LA), a co-factor for metabolic enzymes, suppresses the tumor growth. In this study, we have researched the...
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| Publicado no: | J Ovarian Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4470044/ https://ncbi.nlm.nih.gov/pubmed/26063499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-015-0165-z |
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