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Complement regulator CD46: genetic variants and disease associations
Membrane cofactor protein (MCP; CD46) is an ubiquitously expressed complement regulatory protein that protects host cells from injury by complement. This type-I membrane glycoprotein serves as a cofactor for the serine protease factor I to mediate inactivation of C3b and C4b deposited on host cells....
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| Veröffentlicht in: | Hum Genomics |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469999/ https://ncbi.nlm.nih.gov/pubmed/26054645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0029-z |
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