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Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections

Membrane cofactor protein (MCP; CD46), a ubiquitously expressed complement regulatory protein, serves as a cofactor for serine protease factor I to cleave and inactivate C3b and C4b deposited on host cells. However, CD46 also plays roles in human reproduction, autophagy, modulating T cell activation...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Liszewski, M Kathryn, Atkinson, John P
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123722/
https://ncbi.nlm.nih.gov/pubmed/34004375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2021.04.005
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