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Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections
Membrane cofactor protein (MCP; CD46), a ubiquitously expressed complement regulatory protein, serves as a cofactor for serine protease factor I to cleave and inactivate C3b and C4b deposited on host cells. However, CD46 also plays roles in human reproduction, autophagy, modulating T cell activation...
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| Pubblicato in: | Curr Opin Immunol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier Ltd.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8123722/ https://ncbi.nlm.nih.gov/pubmed/34004375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2021.04.005 |
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