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Complement regulator CD46: genetic variants and disease associations

Membrane cofactor protein (MCP; CD46) is an ubiquitously expressed complement regulatory protein that protects host cells from injury by complement. This type-I membrane glycoprotein serves as a cofactor for the serine protease factor I to mediate inactivation of C3b and C4b deposited on host cells....

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Liszewski, M. Kathryn, Atkinson, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469999/
https://ncbi.nlm.nih.gov/pubmed/26054645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0029-z
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