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Complement Dysregulation and Disease: Insights from Contemporary Genetics

The vertebrate complement system consists of sequentially interacting proteins that provide for a rapid and powerful host defense. Nearly 60 proteins comprise three activation pathways (classical, alternative, and lectin) and a terminal cytolytic pathway common to all. Attesting to its potency, near...

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Detalhes bibliográficos
Publicado no:Annu Rev Pathol
Main Authors: Liszewski, M. Kathryn, Java, Anuja, Schramm, Elizabeth C., Atkinson, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020056/
https://ncbi.nlm.nih.gov/pubmed/27959629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-012615-044145
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