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Complement Dysregulation and Disease: Insights from Contemporary Genetics
The vertebrate complement system consists of sequentially interacting proteins that provide for a rapid and powerful host defense. Nearly 60 proteins comprise three activation pathways (classical, alternative, and lectin) and a terminal cytolytic pathway common to all. Attesting to its potency, near...
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Publicado no: | Annu Rev Pathol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6020056/ https://ncbi.nlm.nih.gov/pubmed/27959629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathol-012615-044145 |
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