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Evolution of the complement system: from defense of the single cell to guardian of the intravascular space

The complement system is an evolutionarily ancient component of immunity that revolves around the central component C3. With the recent description of intracellular C3 stores in many types of human cells, our view of the complement system has expanded. In this article, we hypothesize that a primitiv...

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Dades bibliogràfiques
Publicat a:Immunol Rev
Autors principals: Elvington, Michelle, Liszewski, M. Kathryn, Atkinson, John P.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108576/
https://ncbi.nlm.nih.gov/pubmed/27782327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12474
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