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Diastereo- and Enantioselective Iridium Catalyzed Coupling of Vinyl Aziridines and Alcohols: Site-Selective Modification of Unprotected Diols and Synthesis of Substituted Piperidines

The chiral cyclometalated π-allyliridium ortho-C,O-benzoate complex (R)-Ir-VIb derived from [Ir(cod)Cl](2), allyl acetate, 4-cyano-3-nitrobenzoic acid, and (R)-MeO-BIPHEP catalyzes the coupling of N-(p-nitrophenylsulfonyl) protected vinyl aziridine 3a with primary alcohols 1a–1l to furnish branched...

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Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Wang, Gang, Franke, Jana, Ngo, Chinh Q., Krische, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469948/
https://ncbi.nlm.nih.gov/pubmed/26074091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04404
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