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Modeling of the OX(1)R–orexin-A complex suggests two alternative binding modes
BACKGROUND: Interactions between the orexin peptides and their cognate OX(1) and OX(2) receptors remain poorly characterized. Site-directed mutagenesis studies on orexin peptides and receptors have indicated amino acids important for ligand binding and receptor activation. However, a better understa...
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| Publicado no: | BMC Struct Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469407/ https://ncbi.nlm.nih.gov/pubmed/25957175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-015-0036-2 |
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