Kinetic properties of “dual” orexin receptor antagonists at OX(1)R and OX(2)R orexin receptors

Orexin receptor antagonists represent attractive targets for the development of drugs for the treatment of insomnia. Both efficacy and safety are crucial in clinical settings and thorough investigations of pharmacokinetics and pharmacodynamics can predict contributing factors such as duration of act...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Callander, Gabrielle E., Olorunda, Morenike, Monna, Dominique, Schuepbach, Edi, Langenegger, Daniel, Betschart, Claudia, Hintermann, Samuel, Behnke, Dirk, Cotesta, Simona, Fendt, Markus, Laue, Grit, Ofner, Silvio, Briard, Emmanuelle, Gee, Christine E., Jacobson, Laura H., Hoyer, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847553/
https://ncbi.nlm.nih.gov/pubmed/24376396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2013.00230
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados