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Distinct effects of IPSU and suvorexant on mouse sleep architecture
Dual orexin receptor (OXR) antagonists (DORAs) such as almorexant, SB-649868, suvorexant (MK-4305), and filorexant (MK-6096), have shown promise for the treatment of insomnias and sleep disorders. Whether antagonism of both OX(1)R and OX(2)R is necessary for sleep induction has been a matter of some...
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| Glavni autori: | , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857892/ https://ncbi.nlm.nih.gov/pubmed/24368893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2013.00235 |
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