Distinct effects of IPSU and suvorexant on mouse sleep architecture

Dual orexin receptor (OXR) antagonists (DORAs) such as almorexant, SB-649868, suvorexant (MK-4305), and filorexant (MK-6096), have shown promise for the treatment of insomnias and sleep disorders. Whether antagonism of both OX(1)R and OX(2)R is necessary for sleep induction has been a matter of some...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hoyer, Daniel, Dürst, Thomas, Fendt, Markus, Jacobson, Laura H., Betschart, Claudia, Hintermann, Samuel, Behnke, Dirk, Cotesta, Simona, Laue, Grit, Ofner, Silvio, Legangneux, Eric, Gee, Christine E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2013
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857892/
https://ncbi.nlm.nih.gov/pubmed/24368893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2013.00235
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg