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Dose proportionality and pharmacokinetics of carvedilol sustained-release formulation: a single dose-ascending 10-sequence incomplete block study
BACKGROUND: Carvedilol is a third-generation β-blocker indicated for congestive heart failure and high blood pressure. The aim of this study was to investigate the dose proportionality of the carvedilol sustained-release (SR) formulation in healthy male subjects. METHODS: An open-label, single dose-...
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| Published in: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Dove Medical Press
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468955/ https://ncbi.nlm.nih.gov/pubmed/26089641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86168 |
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