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Cross-Protection of Influenza A Virus Infection by a DNA Aptamer Targeting the PA Endonuclease Domain
Amino acid residues in the N-terminal of the PA subunit (PA(N)) of the influenza A virus polymerase play critical roles in endonuclease activity, protein stability, and viral RNA (vRNA) promoter binding. In addition, PA(N) is highly conserved among different subtypes of influenza virus, which sugges...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468670/ https://ncbi.nlm.nih.gov/pubmed/25918143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00306-15 |
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