Cross-Protection of Influenza A Virus Infection by a DNA Aptamer Targeting the PA Endonuclease Domain

Amino acid residues in the N-terminal of the PA subunit (PA(N)) of the influenza A virus polymerase play critical roles in endonuclease activity, protein stability, and viral RNA (vRNA) promoter binding. In addition, PA(N) is highly conserved among different subtypes of influenza virus, which sugges...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Yuan, Shuofeng, Zhang, Naru, Singh, Kailash, Shuai, Huiping, Chu, Hin, Zhou, Jie, Chow, Billy K. C., Zheng, Bo-Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468670/
https://ncbi.nlm.nih.gov/pubmed/25918143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00306-15
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky