EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway

The elongation factor Tu GTP binding domain-containing protein 2 (EFTUD2) was identified as an anti-hepatitis C virus (HCV) host factor in our recent genome-wide small interfering RNA (siRNA) screen. In this study, we sought to further determine EFTUD2's role in HCV infection and investigate th...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhu, Chuanlong, Xiao, Fei, Hong, Jian, Wang, Kun, Liu, Xiao, Cai, Dachuan, Fusco, Dahlene N., Zhao, Lei, Jeong, Soung Won, Brisac, Cynthia, Chusri, Pattranuch, Schaefer, Esperance A., Zhao, Hong, Peng, Lee F., Lin, Wenyu, Chung, Raymond T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468487/
https://ncbi.nlm.nih.gov/pubmed/25878102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00364-15
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