Particle-to-PFU Ratio of Ebola Virus Influences Disease Course and Survival in Cynomolgus Macaques

This study addresses the role of Ebola virus (EBOV) specific infectivity in virulence. Filoviruses are highly lethal, enveloped, single-stranded negative-sense RNA viruses that can cause hemorrhagic fever. No approved vaccines or therapies exist for filovirus infections, and infectious virus must be...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Alfson, Kendra J., Avena, Laura E., Beadles, Michael W., Staples, Hilary, Nunneley, Jerritt W., Ticer, Anysha, Dick, Edward J., Owston, Michael A., Reed, Christopher, Patterson, Jean L., Carrion, Ricardo, Griffiths, Anthony
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Pathogenesis and Immunity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468478/
https://ncbi.nlm.nih.gov/pubmed/25903348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00649-15
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