Particle-to-PFU Ratio of Ebola Virus Influences Disease Course and Survival in Cynomolgus Macaques

This study addresses the role of Ebola virus (EBOV) specific infectivity in virulence. Filoviruses are highly lethal, enveloped, single-stranded negative-sense RNA viruses that can cause hemorrhagic fever. No approved vaccines or therapies exist for filovirus infections, and infectious virus must be...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Alfson, Kendra J., Avena, Laura E., Beadles, Michael W., Staples, Hilary, Nunneley, Jerritt W., Ticer, Anysha, Dick, Edward J., Owston, Michael A., Reed, Christopher, Patterson, Jean L., Carrion, Ricardo, Griffiths, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468478/
https://ncbi.nlm.nih.gov/pubmed/25903348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00649-15
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