Characterization of Immune Responses Induced by Ebola Virus Glycoprotein (GP) and Truncated GP Isoform DNA Vaccines and Protection Against Lethal Ebola Virus Challenge in Mice

In addition to its surface glycoprotein (GP), Ebola virus directs the production of large quantities of a truncated glycoprotein isoform (sGP) that is secreted into the extracellular space. We recently reported that sGP actively diverts host antibody responses against the epitopes that it shares wit...

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Veröffentlicht in:J Infect Dis
Hauptverfasser: Li, Wenfang, Ye, Ling, Carrion, Ricardo, Mohan, Gopi S., Nunneley, Jerritt, Staples, Hilary, Ticer, Anysha, Patterson, Jean L., Compans, Richard W., Yang, Chinglai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564543/
https://ncbi.nlm.nih.gov/pubmed/25877553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv186
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