Particle-to-PFU Ratio of Ebola Virus Influences Disease Course and Survival in Cynomolgus Macaques

This study addresses the role of Ebola virus (EBOV) specific infectivity in virulence. Filoviruses are highly lethal, enveloped, single-stranded negative-sense RNA viruses that can cause hemorrhagic fever. No approved vaccines or therapies exist for filovirus infections, and infectious virus must be...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Alfson, Kendra J., Avena, Laura E., Beadles, Michael W., Staples, Hilary, Nunneley, Jerritt W., Ticer, Anysha, Dick, Edward J., Owston, Michael A., Reed, Christopher, Patterson, Jean L., Carrion, Ricardo, Griffiths, Anthony
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468478/
https://ncbi.nlm.nih.gov/pubmed/25903348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00649-15
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