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Impact of heparanase on renal fibrosis

Tubulo-interstitial fibrosis has been recognized as the hallmark of progression of chronic kidney disease, but, despite intensive research studies, there are currently no biomarkers or effective treatments for this condition. In this context, a promising candidate could be heparanase-1 (HPSE), an en...

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Bibliographic Details
Published in:J Transl Med
Main Authors: Masola, Valentina, Zaza, Gianluigi, Onisto, Maurizio, Lupo, Antonio, Gambaro, Giovanni
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467599/
https://ncbi.nlm.nih.gov/pubmed/26040666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0538-5
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