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CD2 Costimulation Reveals Defective Activity by Human CD4(+)CD25(hi) Regulatory Cells in Patients with Multiple Sclerosis

Studying the activity of homogeneous regulatory T cell (Treg) populations will advance our understanding of their mechanisms of action and their role in human disease. Although isolating human Tregs exhibiting low expression of CD127 markedly increases purity, the resulting Treg populations are stil...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Baecher-Allan, Clare M., Costantino, Cristina M., Cvetanovich, Gregory L., Ashley, Charles W., Beriou, Gaëlle, Dominguez-Villar, Margarita, Hafler, David A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467560/
https://ncbi.nlm.nih.gov/pubmed/21300823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002502
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