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CD2 Costimulation Reveals Defective Activity by Human CD4(+)CD25(hi) Regulatory Cells in Patients with Multiple Sclerosis

Studying the activity of homogeneous regulatory T cell (Treg) populations will advance our understanding of their mechanisms of action and their role in human disease. Although isolating human Tregs exhibiting low expression of CD127 markedly increases purity, the resulting Treg populations are stil...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Baecher-Allan, Clare M., Costantino, Cristina M., Cvetanovich, Gregory L., Ashley, Charles W., Beriou, Gaëlle, Dominguez-Villar, Margarita, Hafler, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467560/
https://ncbi.nlm.nih.gov/pubmed/21300823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002502
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