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Identification of T helper type 1–like, Foxp3(+) regulatory T cells in human autoimmune disease

CD4(+)CD25(high)CD127(low/−) forkhead box p3 (Foxp3)(+) regulatory T cells (T(reg) cells) possess functional plasticity. Here we describe a higher frequency of T helper type 1 (T(H)1)-like, interferon-γ (IFN-γ)-secreting Foxp3(+) T cells in untreated subjects with relapsing remitting multiple sclero...

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Detalhes bibliográficos
Main Authors: Dominguez-Villar, Margarita, Baecher-Allan, Clare M, A Hafler, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675886/
https://ncbi.nlm.nih.gov/pubmed/21540856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2389
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