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Enhanced Suppressor Function of TIM-3(+) FoxP3(+) Regulatory T cells

T cell Immunoglobulin and Mucin domain 3 (TIM-3) is an Ig superfamily member expressed on IFNγ-secreting Th1 and Tc1 cells identified as a negative regulator of immune tolerance. TIM-3 is expressed by a subset of activated CD4(+) T cells, and anti-CD3/anti-CD28 stimulation increases both the level o...

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Hlavní autoři: Gautron, Anne-Sophie, Dominguez-Villar, Margarita, de Marcken, Marine, Hafler, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165702/
https://ncbi.nlm.nih.gov/pubmed/24838857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344392
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