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Enhanced Suppressor Function of TIM-3(+) FoxP3(+) Regulatory T cells
T cell Immunoglobulin and Mucin domain 3 (TIM-3) is an Ig superfamily member expressed on IFNγ-secreting Th1 and Tc1 cells identified as a negative regulator of immune tolerance. TIM-3 is expressed by a subset of activated CD4(+) T cells, and anti-CD3/anti-CD28 stimulation increases both the level o...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4165702/ https://ncbi.nlm.nih.gov/pubmed/24838857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344392 |
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