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High throughput strategy to identify inhibitors of histone-binding domains

Many epigenetic proteins recognize the posttranslational modification state of chromatin through their histone binding domains, and thereby recruit nuclear complexes to specific loci within the genome. A number of these domains have been implicated in cancer and other diseases through aberrant bindi...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Wagner, Elise K., Albaugh, Brittany N., Denu, John M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467374/
https://ncbi.nlm.nih.gov/pubmed/22910207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-391940-3.00008-1
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