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Kinetic mechanism of histone acetyltransferase and chaperone complex, Rtt109-Vps75

Rtt109 is a histone acetyltransferase (HAT) involved in promoting genomic stability, DNA repair and transcriptional regulation. Rtt109 associates with the NAP1 family histone chaperone Vps75, and stimulates histone acetylation. Here we explore the mechanism of histone acetylation and report a detail...

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Detalhes bibliográficos
Main Authors: Albaugh, Brittany N., Kolonko, Erin M., Denu, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917178/
https://ncbi.nlm.nih.gov/pubmed/20560668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100381y
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