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Kinetic mechanism of histone acetyltransferase and chaperone complex, Rtt109-Vps75

Rtt109 is a histone acetyltransferase (HAT) involved in promoting genomic stability, DNA repair and transcriptional regulation. Rtt109 associates with the NAP1 family histone chaperone Vps75, and stimulates histone acetylation. Here we explore the mechanism of histone acetylation and report a detail...

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Bibliografiske detaljer
Main Authors: Albaugh, Brittany N., Kolonko, Erin M., Denu, John M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917178/
https://ncbi.nlm.nih.gov/pubmed/20560668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100381y
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