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Kinetic mechanism of histone acetyltransferase and chaperone complex, Rtt109-Vps75

Rtt109 is a histone acetyltransferase (HAT) involved in promoting genomic stability, DNA repair and transcriptional regulation. Rtt109 associates with the NAP1 family histone chaperone Vps75, and stimulates histone acetylation. Here we explore the mechanism of histone acetylation and report a detail...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Albaugh, Brittany N., Kolonko, Erin M., Denu, John M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917178/
https://ncbi.nlm.nih.gov/pubmed/20560668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100381y
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